top of page
test bekrund (22)_edited_edited.jpg

Ready to start learning about Photobiomodutation?

Although light (Photon) therapy has been documented in medical literature as early as 1500 BC, it was the Danish physician Nils Finsen, who is believed to be the father of phototherapy that received a Nobel Prize for his work in 1903. Since then, numerous authors have advocated treatment by phototherapy for many different diseases ranging from acne, vitiligo, jaundice in babies, wound healing, and rheumatoid arthritis to name only a few. 
Photobiomodulation (PBM Therapy) previously known as Low-Level Laser Therapy (LLLT) is a laser or LED light therapy that improves tissue repair (skin wounds, muscle, tendon, bone, nerves), reduces inflammation, and reduces pain wherever the beam is applied. 

Photobiomodulation (PBM) is the term used to describe the mechanics/scientific basis for this photonic specialty and photobiomodulation therapy (PBMT) as the term for its therapeutic application. PBMT was first developed in the 1960s. During the early years, this emerging photonic application was plagued by several problems including inconsistent terminology. Many terms were introduced such as Biostimulation, Cold/Cool Laser, Low-Level laser therapy, Soft Laser, and Low Power Laser Therapy. Based on recent consensus in the field, PBM and PBMT now consider the terms of choice.  In 2015 thanks to the efforts of Dr. Praveen Arany, PBMT was added to the National Library of Medicine MeSH database as an entry term to the existing record of laser therapy, low-level. In summary, PBM and PBMT are accurate and specific terms of this effective and important therapeutic application of light. 

What devices are used?

A suggested definition for PBMT is a form of light therapy that utilizes non-ionizing forms of light sources, including LASERS, LEDs, and broadband light, in the visible and near-infrared spectrum. It is a non-thermal process involving endogenous chromophores eliciting photophysical and photochemical events at various biological scales. PBM devices have been cleared for marketing by FDA through the Premarket Notification/510(k) process as adjunctive devices for the temporary relief of pain. These clearances were based on the presentation of clinical data to support such claims.

Michael Hamblin, PhD

Principal Investigator, Wellman Center for Photomedicine at Massachusetts General Hospital | Associate Professor, Dermatology, Harvard Medical School


Dr. Hamblin's research interests are now broadly in the area of phototherapy for multiple diseases


He has published 422 peer-reviewed articles, is Editor in Chief of "Photoiomodulation, Photomedicine and Laser Surgery" and Associate Editor for 10 journals. He has an h-factor 93 and >33,000 citations. He has authored/edited 23 textbooks on PDT and photomedicine including SPIE proceedings.

Dr Hamblin was elected as a Fellow of SPIE in 2011, received 1st Endre Mester Lifetime Achievement Award Photomedicine from NAALT in 2017, Outstanding Career Award from Dose Response Society and 1st Ali Javan Award for Basic Research from WALT in 2018.

Science. Not magic.

Red Light Therapy has been studied in over 500 human trials and 10.000 laboratory studies.

Photizo by Caball  has been shown to stimulate cells and heal wounds and represents a new era in healing, and wound treatment. Photizo® is lightweight, portable, and can work off batteries or mains power, thereby representing a new era in healing using light therapy.

A Short Histrory Of Light Therapy 

The use of light therapy in treatment and healing is not a new concept – the Nobel prize was awarded to Niels Ryberg Finsen in 1903 for his work on red-light therapy in healing smallpox and lupus. During the 1960’s, laser-based light therapy was used in many clinical and experimental settings and was responsible for great breakthroughs in non-invasive treatment of illnesses. A further breakthrough occurred in the 1990’s when NASA began working on the use of light emitting diode (LED)-based light therapy units for use in wound healing in astronauts, as wounds take longer to heal in zero-gravity conditions. Their research paved the way for the PhotizoTM light therapy device, which takes the best of currently available light therapy machines and combines them into one, easy to use, and portable healing system.

Clinical Trials and Studies

Is there a difference in the effect of Laser and LEDs?

Low-energy laser therapy: Controversies and new research findings

Shining light on the head: photobiomodulation for brain disorders

Mechanisms and mitochondrial redox signaling in photobiomodulation

Proposed mechanisms of photobiomodulation or low-level light therapy

Photobiomodulation: lasers vs. light emitting diodes?

Photobiomodulation for Alzheimer's disease: Translating basic research to clinical application

… nm) or near-infrared (810 nm) photobiomodulation stimulates, while blue (415 nm), green (540 nm)

light inhibits proliferation in human adipose-derived stem …

Photobiomodulation in human muscle tissue: an advantage in sports performance?

Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action …

Photobiomodulation and cancer: what is the truth?

Mechanistic aspects of photobiomodulation therapy in the nervous system

Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis

Photobiomodulation for traumatic brain injury and stroke

Applications of photobiomodulation therapy to musculoskeletal disorders and osteoarthritis with particular relevance to Canada

Probable positive effects of the photobiomodulation as an adjunctive treatment in COVID-19: A systematic review

Rapid reversal of cognitive decline, olfactory dysfunction, and quality of life using multi-modality photobiomodulation therapy: case report

Mechanisms and mitochondrial redox signaling in photobiomodulation

[HTML] Photobiomodulation for the management of alopecia: mechanisms of action, patient selection and perspectives

[HTML] The use of low level laser therapy (LLLT) for musculoskeletal pain

Significant improvement in cognition in mild to moderately severe dementia cases treated with transcranial plus intranasal photobiomodulation: case series report

Low-level laser therapy for chronic non-specific low back pain: a meta-analysis of randomised controlled trials

Long-term survival of a randomized phase III trial of head and neck cancer patients receiving concurrent chemoradiation therapy with or without low-level laser therapy (LLLT) to prevent oral mucositis

Cost-effectiveness of the introduction of specialized oral care with laser therapy in hematopoietic stem cell transplantation

A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis


Frozen shoulder: the effectiveness of conservative and surgical interventions--systematic review

Immediate effect of photobiomodulation therapy on Achilles tendon morphology and mechanical properties: an exploratory study
Photobiomodulation Therapy in Hearing Related Aspects
Efficacy of Low-Level Laser Therapy in Subjective Tinnitus Patients with Temporomandibular DisordersASSESSMENT OF THE PRACTICAL RESPONSE TO TREATING COLIC WITH ACUPUNCTURE IN ARABIAN HORSES

Follow us on Social Media

  • Instagram
  • Facebook
  • YouTube
  • Tiktok

Caball Therapy Systems
Skaarupore Strandvej 52C
5881 Skaarup Fyn

+45 2815 5676

© 2023 by Feelgoodfunnels  for CTS.    COPYRIGHT ©

bottom of page